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Combining a known independent risk factor with a medication carrying a pancreatitis warning warrants caution, particularly for heavy drinkers

Orthotopic xenografts were generated by implanting 2.5 million MDA-MB-231 cells in 100 L phosphate-buffered saline (PBS) mixed with 100 L growth factor-reduced Matrigel (Corning) bilaterally into the fourth inguinal fat pad of four- to six-week-old female NOD

Safety : Generally safe when administered by professionals, with mild and temporary side effects like injection-site irritation

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The decision notably carries immediate relevance for plan sponsors and benefits administrators